Enright strained the medial ligament in his right knee in the qualifying final against Fremantle.
He went through a solid running session on Tuesday and the club refused to rule him out, but football manager Neil Balme confirmed on Wednesday that he would not play.
"He's come in pretty well this week, but we won't be playing him this week," Balme told reporters at Simonds Stadium.
Balme said the Cats were pretty content with how he was recovering, but were not making any decisions on his availability for the Grand Final if the Cats defeat the Hawks.
"That's another question for another day, but we're pretty happy with the way he's going."
Tom Hawkins did hit the track on Wednesday and went through some gentle run-throughs and light kicking as he manages his ongoing back issue.
"What do we say, good today, I hope it's good tomorrow and the next day. But, no, he's been pretty good actually, so we're pretty confident (he'll play)," Balme said.
Josh Caddy trained strongly and "should be fine" if recalled, while youngsters Jordan Murdoch and potential debutant Shane Kersten, alongside Caddy, are the favourites to replace the suspended Paul Chapman.
Balme also questioned how the Match Review Panel has assessed players bumping this season.
Chapman will miss this Friday night's blockbuster after accepting his one-match suspension for engaging in rough conduct on Port Adelaide's Robbie Gray.
The Cats' football manager said the system, which the League has recently put under review, "had gone too far".
"It's very hard to take the automatic response out of it (the bump)," Balme said.
"But the rule says that if you choose to bump someone, if anything happens it's your fault.
"You could argue forever whether that's reasonable, and I think it's not, but that's the way it is.
"You just can't bump in my view - and everyone at AFL House says the bump's not out of the game, well, I think, effectively it is."
Balme also said the Cats expected Hawk Cyril Rioli to take his place in the Hawks side on Friday night, as he does everything in his power to overcome an ankle complaint.
